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Synergy: A Web Resource for Exploring Gene Regulation in Synechocystis sp. PCC6803

Figure 4

Gene co-expression neighborhoods with significant motif enrichment.

The figure plots the fraction of neighborhoods for regulatory genes (A) and DNA-binding genes (B) with at least one significantly enriched motif (q<0.05) against the q-value threshold for mapping motifs to the genome. The fractions are calculated from the total number of genes in the respective groups that have gene expression data (118 DNA-binding genes and 136 regulatory genes). Plots are shown for all motifs and the subset of central motifs as well as for the complete and subset co-expression networks with different CLR thresholds. P-values are given for each combination of parameters and indicate the probability of observing the reported fraction of enriched neighborhoods in randomized networks.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0113496.g004