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OxMaR: Open Source Free Software for Online Minimization and Randomization for Clinical Trials

Figure 3

Array used to contain new participant information.

The upper panel shows the information in the form that is inputted by the user through the first web page (Web Page 1). When this information is confirmed the second Perl script then parses this information and constructs an array of the form shown. Several variables, such as the participant ID number and date, are included in the array, but are not all shown as they do not play a role in the allocation procedure and serve a purely documentary role. For each variable that is factored into the allocation algorithm, an array element is created for each of the possible options for this variable. Therefore, there are two array elements for gender, one for male and one for female. For a female participant, the value of the element for male will be 0 and the value of the element for female will be 1 as shown. It should be noted that for each variable such as age, gender or ethnicity only one of the value options can be 1 and all others will be 0. The array also contains two elements that will encode the group to which the participant has been allocated. When the array is first created both elements are set to 0, but if, as shown here, the participant is allocated to the control group, then the value of the control group element will then be changed to 1.

Figure 3