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Evaluation of a Novel Magneto-Optical Method for the Detection of Malaria Parasites

Figure 1

Distribution of parasite life cycle stages in the two Plasmodium falciparum cultures used in the present study.

Panel A: The ring stage culture contained early rings, late rings and some early trophozoites of the first generation after synchronization. The schizont stage culture was on the verge of the first and second life cycles where most of the schizont stages have already turned to early ring stages of the second generation following invasion. Therefore, the ring stage culture contained only the hemozoin present in the parasites up to the early trophozoite stage, while the schizont stage culture had the entire hemozoin content formed during one generation of parasites with the largest portion produced by schizonts. Panel B: Light microscopy images of Giemsa stained thin blood films containing infected red blood cells with parasites in different stages of maturity (taken from these two cultures). In both panels the labels ER, LR, ET, LT, ES and LS correspond to early-ring, late-ring, early-trophozoite, late-trophozoite, early-schizont and late-schizont stages, respectively.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0096981.g001