Signaling Properties and Pharmacological Analysis of Two Sulfakinin Receptors from the Red Flour Beetle, Tribolium castaneum
Figure 3
Dose response curves for bioluminescence induced by sTrica-SK(5–13) and sLocmi-SK in Trica-SKR expressing CHO-WTA11 cells.
Aequorin bioluminescence induced in CHO-WTA11 cells stably expressing the promiscuous Gα16 subunit and transfected with Trica-SKR1 (A) or Trica-SKR2 (B). Receptor activation shown as the percentage of activation achieved with 1 μM sTrica-SK(5–13) (maximal response level = 100%). The zero response level corresponds to treatment of cells with DMEM/BSA. Data represent the mean ± SEM of three independent measurements (each performed in duplicate).