Inhibition of Fatty Acid Binding Proteins Elevates Brain Anandamide Levels and Produces Analgesia
Figure 5
Activation of PPARα by FABP inhibitors.
HeLa cells transfected with a PPARα reporter were incubated with the indicated compounds for 6 hours and luciferase and β-galactosidase activities were subsequently measured. Luciferase activity was normalized to β-galactosidase. The blue line represents baseline PPARα activation in the absence of agonists (n = 3).