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Antifungal Activity of Naphthoquinoidal Compounds In Vitro against Fluconazole-Resistant Strains of Different Candida Species: A Special Emphasis on Mechanisms of Action on Candida tropicalis

Figure 3

An analysis of changes in cell size/granularity (FSC×SSC) to evaluate the effects of fluconazole (64 µg/mL), Ampho (4 µg/mL) and naphthofuranquinone (NFQ) compounds 1, 2 and 3 at concentrations of 32 µg/mL (a); 64 µg/mL (b) and 128 µg/mL (c) on isolates of FLC-resistant C. tropicalis after a 24 h incubation.

* p<0.05 compared to the control using an ANOVA followed by the Newman-Keuls test.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0093698.g003