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Epithelial SCAP/INSIG/SREBP Signaling Regulates Multiple Biological Processes during Perinatal Lung Maturation

Figure 5

Putative SREBP co-factors mediating perinatal lung lipid homeostasis.

A SREBP related transcriptional network was constructed based on the promoter analysis of genes within Clusters 5 and 7. Each connection between a matrix family (white rectangle) and a target gene (blue oval) represents at least one predicted binding site for a given transcription factor on the promoter region of that target gene.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0091376.g005