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Mesenchymal Stem Cells Modulate Albumin-Induced Renal Tubular Inflammation and Fibrosis

Figure 1

Tri-lineage differentiation capacities of BM-MSCs upon exposure to albumin.

BM-MSCs were incubated with or without HSA for 24 h prior to induction of differentiation. Osteogenic differentiation was evidenced by Alizarin Red staining of mineralization (top panels) at day 21. Oil droplet stained by Oil-Red-O revealed adipogenic differentiation (middle panels) at day 14. Chondrogenic differentiation was demonstrated by toluidine blue staining of extracellular matrix formation (bottom panels) at day 14.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0090883.g001