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The CO-Regulation Database (CORD): A Tool to Identify Coordinately Expressed Genes

Figure 5

CORD results for MYOD1.

A) The differentiation of muscle stem cells (satellite cells) to myoblasts and ultimately to skeletal muscle is under the control of muscle regulatory factors including the transcription factor MyoD. CORD output for MYOD1 demonstrates co- expression of other muscle regulatory factors like myogenin (MYOG) and many genes implicated in muscle differentiation. B) The MyoD1 correlated genes were over representative for several KEGG pathways relating to muscle such as “Cardiac muscle contraction” and “Dilated cardiomyopathy.”

Figure 5

doi: https://doi.org/10.1371/journal.pone.0090408.g005