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A Prognostic Gene Signature for Metastasis-Free Survival of Triple Negative Breast Cancer Patients

Figure 3

The BPMS is a single patient predictor.

Using frozen RMA pre-processed data, the BPMS was trained to be applied on a patient-to-patient basis. The BrCa871 set was processed using fRMA, divided into the BrCa436-Train and BrCa435-CV sets and 7,500 potential solutions were optimized. Using a cross-validation strategy, a final set of BPMS parameters were trained for fRMA processed data. Shown is the application of these parameters to the fRMA processed BrCa341 data set.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0082125.g003