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A Prognostic Gene Signature for Metastasis-Free Survival of Triple Negative Breast Cancer Patients

Figure 1

The optimized solutions yield larger cohort sizes and better p-values.

Distribution density plots for non-optimized (control) and optimized signatures verify that significantly better cohort sizes (A) and p-values (B) were generated using a cost function in conjunction with the Nelder-Mead optimization algorithm.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0082125.g001