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Proteomic Changes during B Cell Maturation: 2D-DIGE Approach

Figure 1

PID-related proteins in B cell maturation pathway.

Defects in proteins and genes important for maturation cause PIDs and block the maturation on certain stage. The PID-related proteins and stages where diseases affect the development are shown on top. The cell lines (RS4;11, 380, REH, 697, Nalm-1, Nalm-6, Ramos and U-266) are marked inside the corresponding cells representing their normal B cell counterparts.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0077894.g001