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Ablation of the Id2 Gene Results in Altered Circadian Feeding Behavior, and Sex-Specific Enhancement of Insulin Sensitivity and Elevated Glucose Uptake in Skeletal Muscle and Brown Adipose Tissue

Figure 5

Fasting glucose and Insulin levels while aging.

A) Fasting blood glucose levels of young and old, WT and Id2−/− mice (ANOVA: genotype, P<0.01; age, P<0.001; interaction, n.s.). B). Fasting insulin levels of young and old, WT and Id2−/− mice (genotype, P<0.001; age, P<0.05; interaction, n.s.). Values shown represent mean ± SEM. *p<0.05, **p<0.01 and ***p<0.001.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0073064.g005