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Ablation of the Id2 Gene Results in Altered Circadian Feeding Behavior, and Sex-Specific Enhancement of Insulin Sensitivity and Elevated Glucose Uptake in Skeletal Muscle and Brown Adipose Tissue

Figure 4

Cell size of the gonadal white adipose tissue is different between female Id2−/− and WT mice.

A) Representative images of hematoxylin/eosin stained gonadal white adipose tissue sections of male and female WT and Id2−/− mice (scale bar = 50 µm). B) Cell area of gonadal WAT in WT and Id2−/− mice (ANOVA: genotype, P<0.05; sex, n.s.; interaction, P<0.001). No significant correlation was detected between cell size and age of animal (Spearman’s rank order correlation/linear regression, n.s.).

Figure 4

doi: https://doi.org/10.1371/journal.pone.0073064.g004