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The Extraction of Simple Relationships in Growth Factor-Specific Multiple-Input and Multiple-Output Systems in Cell-Fate Decisions by Backward Elimination PLS Regression

Figure 7

The simple relationships in the MIMO system in cell fate decision in PC12 cells.

(A) The simple PLS model with 5 input and 9 output variables. (B) Loadings (squares) and scores (circles) of the first and second principal components in the simple PLS model with 5 input and 9 output variables were bi-plotted in input and output layers. Lines across the layers are coefficients of the matrix of the simple PLS model whose values are indicated by the color bar. The colors of circles indicate the stimuli.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0072780.g007