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The Extraction of Simple Relationships in Growth Factor-Specific Multiple-Input and Multiple-Output Systems in Cell-Fate Decisions by Backward Elimination PLS Regression

Figure 4

Validation of the PLS model using inhibitor experiments.

Correlation plots between the measured outputs and predicted outputs with NGF (A), PACAP (B) and anisomycin (C). The correlation coefficient, r, is indicated in each plot. Each dot represents a single time point. The data sets with PD0325901 (MEK inhibitor), H89 (PKA inhibitor), LY294002 (PI3K inhibitor), SB203580 (p38 inhibitor), SP600125 (JNK inhibitor) (Table S2) are indicated by the various colors.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0072780.g004