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Dynamic Simulation and Metabolome Analysis of Long-Term Erythrocyte Storage in Adenine–Guanosine Solution

Figure 5

Prediction of intracellular metabolite levels depending on the combination of initial adenine and guanine concentrations.

Predicted concentrations of ATP (left column), 2,3-BPG (center column), and total HX (right column) at 7, 14, 28, and 35 days after storage in various combinations of ADE and GUO concentrations. In each panel, the x and y axes represent initial concentration of ADE and GUO in the model, respectively. The initial setting of ADE and GUO varied between 0 to 3 mM.

Figure 5