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Dynamic Simulation and Metabolome Analysis of Long-Term Erythrocyte Storage in Adenine–Guanosine Solution

Figure 1

Pathway reactions in the mathematical model of PAGGGM-stored RBCs.

Nodes indicate metabolites or ions, and edges indicate enzymatic reactions or transport processes, which were divided into 3 groups (red, blue, gray boxes) by the difference in sensitivity of enzymatic or reaction activity to temperature or pH as described in our previous study [9]. Abbreviations used in this figure are given in Table 1.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0071060.g001