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LifeMap Discovery™: The Embryonic Development, Stem Cells, and Regenerative Medicine Research Portal

Figure 4

Branchial Arch 1 (HdM.BA1) anatomical compartment development card.

A. Anatomical compartment viewer demonstrating the contribution of ‘Head Mesoderm’ and ‘Cranial Neural Crest’ to the developing ‘Head Mesenchyme’, which give rise to Branchial Arch 1 and its functional derivatives (i.e., cartilage, bone and skeletal muscles), is depicted in this viewer (highlighted, orange colored boxes). B. Illustration showing the embryonic ontology and development of the two main cellular components (i.e., paraxial mesoderm and neural crest cells) which give rise to skeletal elements of the head (lateral view). Such anatomical illustrations are available in the database at the organ/tissue and anatomical compartment cards C. Examples of the display of selective gene markers of cells populating the anatomical compartment. Here the selective genes of CNC cells and Paraxial Mesoderm cells are shown in the BA1 anatomical compartment card. Abbreviations: mb, midbrain; fb, forebrain;r1–7, rhombomeres 1–7; HdM.BA1–4, branchial arch 1–4; OV, optic vesicle.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0066629.g004