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EffiCiency and Safety of an eLectronic cigAreTte (ECLAT) as Tobacco Cigarettes Substitute: A Prospective 12-Month Randomized Control Design Study

Figure 1

Flow of participants.

After screening for the study inclusion/exclusion criteria, a total of 300 regular smokers consented to participate and were included in the study. Participants were randomized into three separate study groups (A, B, and C). Participants randomized in study group A received 12 weeks supply of “Original” 7.2 mg nicotine cartridges; those in study group B, two 6-week supplies of cartridges, one of the “Original” 7.2 mg nicotine cartridges and a further 6 weeks with supply of “Categoria” 5.4 mg nicotine cartridges; participants in study group C received 12 weeks supply of no-nicotine cartridges (i.e. control).

Figure 1

doi: https://doi.org/10.1371/journal.pone.0066317.g001