Advertisement
Browse Subject Areas
?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

< Back to Article

Alternative Computational Protocols for Supercharging Protein Surfaces for Reversible Unfolding and Retention of Stability

Figure 6

High-charge variant hydrogen bond energy changes per structure (600 total).

In high-charge AvNAPSA designs (AvNAPSA cutoff of 150), removal of hydrogen bonds costs 1.5 to 3 Rosetta energy units per structure (empty bars). In contrast, Rosetta designs with the same net charge preserve hydrogen bonds (solid bars).

Figure 6

doi: https://doi.org/10.1371/journal.pone.0064363.g006