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Regulation of Retinoid-Mediated Signaling Involved in Skin Homeostasis by RAR and RXR Agonists/Antagonists in Mouse Skin

Figure 1

Back skin of mice after treatment with retinoid receptor-specific agonists and antagonists.

Representative photographs of dorsal skin areas from mice topically treated with vehicle control (acetone), or various retinoid receptor-selective agonists or antagonists for 14 days. Note the scaly skin of mice treated with the synthetic RXR agonist or the synthetic RARγ agonist, and appearing most pronounced in the RAR agonist (ATRA) treated group. 1all-trans retinoic acid/ATRA.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0062643.g001