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Reactive Oxygen Species-Activated Nanoprodrug of Ibuprofen for Targeting Traumatic Brain Injury in Mice

Figure 2

Comparing accumulation for IV and IP administration.

The injection of nanoprodrug either IV or IP results in similar accumulation in animals with TBI, while normal animals given nanoprodrug and TBI animals do not show any background flourescence. Brains are oriented with the rostral portion toward the top of the image.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0061819.g002