Advertisement
Browse Subject Areas
?

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

< Back to Article

Imperfect Duplicate Insertions Type of Mutations in Plasmepsin V Modulates Binding Properties of PEXEL Motifs of Export Proteins in Indian Plasmodium vivax

Figure 4

Structural cartoon representations of model of plasmepsin-V of P. vivax.

(A) Complete model with C-terminal trans-membrane domain (purple), the n-terminal pro-domain (lime) inhibiting the complete active site cleft with aspartic acid residue (red) and side chains. (B) Displaying structural changes after the cleavage of c-terminal trans-membrane domain (purple). The N-terminal prodomain peptide (lime) frees complete active site cleft after folding at hinge and competitively interacts with same amino acid residue side chains of the model as that of C-terminal in the native structure.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0060077.g004