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Effect of Acute Stressor and Serotonin Transporter Genotype on Amygdala First Wave Transcriptome in Mice

Figure 1

Elevated plus-maze test.

a) Activity-related measures exemplified as the path length covered during the test. Bars represent the median values and the dots represent the data of each individual animal. b) Anxiety-related behavior measured as the proportion of time spent in open arms. Serotonintransporter knockout mice (5-HTT KO, n = 17) were less active and spent a lower proportion of time on open arms indicating increased anxiety compared to wild-type (5-HTT WT, n = 14) mice. Statistics: Wilcoxon exact rank sum test: ** = P<0.01, *** = P<0.001.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0058880.g001