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Using Bacteria to Determine Protein Kinase Specificity and Predict Target Substrates

Figure 3

Goodness-of-fit of the pLogos derived from ProPeL and actual known kinase substrates versus random substrates.

Average pLogo position weight matrix scores of CK II (red) and PKA (blue) pLogos when scanned against known human substrates from the PhosphoSitePlus database compared to average scores obtained from scanning CK II and PKA pLogos against an equivalent number of random human serine and threonine residues. Error bars represent 95% confidence intervals.

Figure 3