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High Yield Production and Refolding of the Double-Knot Toxin, an Activator of TRPV1 Channels

Figure 6

Activity of K1, K2 and DkTx on TRPV1 channels.

(A) Synthetic K1, K2 and DkTx activate TRPV1 channels. Oocytes were held at −60 mV and toxins were added to the recording chamber. (B) Concentration-dependence for activation of TRPV1 by the toxins.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0051516.g006