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Mathematical Modeling of Sustainable Synaptogenesis by Repetitive Stimuli Suggests Signaling Mechanisms In Vivo

Figure 2

Synapse stabling mechanism.

Drebrin induces the assembly of PSD-95 and AMPAR in dendritic protrusions through F-actin accumulation and stabilization, and causes synaptic maintenance. The color difference of F-actin indicates whether the fiber is stable (red) or unstable (pink).

Figure 2

doi: https://doi.org/10.1371/journal.pone.0051000.g002