Spastin's Microtubule-Binding Properties and Comparison to Katanin
Panel A shows a SDS-gel of co-sedimentation assays with katanin (E309Q mutant, 1 mM ATP) and a constant concentration of microtubules (2 µM; indicated by a dotted line). With increasing katanin concentrations, an increasing amount of protein is co-sedimented with microtubules. Panel B: Plot of the densitometric analysis as in Figure 10. Panel C shows the same experiment for wild type katanin.