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Spastin's Microtubule-Binding Properties and Comparison to Katanin

Figure 1

Domain Organization and Alignment of Spastin and Katanin.

The figure shows a sequence alignment of domains of Drosophila and human spastin, as well as human katanin. The black contour highlights the position of the human spastin linker, residues with a high degree of conservation are red, residues with low degree are blue. The location of the highly basic patch in human spastin is boxed in blue. Above the alignment, the location of the sequence in the context of human spastin is indicated, below the location in human katanin. For details, see text.

Figure 1