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An Approach for the Identification of Targets Specific to Bone Metastasis Using Cancer Genes Interactome and Gene Ontology Analysis

Figure 7

Significantly enriched GO terms for hubs of CGN reflecting their role in generic cancer mechanisms.

The overrepresentation studies of Top75 CGN hubs reflect their role in generic cancer processes and functions. Among the significantly enriched GO terms, 17 represent self-proliferation circuits (light-gray), 20 represent cytostasis and differentiation circuits (dark gray) and 4 represent viability circuits (black).

Figure 7

doi: https://doi.org/10.1371/journal.pone.0049401.g007