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An Approach for the Identification of Targets Specific to Bone Metastasis Using Cancer Genes Interactome and Gene Ontology Analysis

Figure 4

Scale-free nature of degree and betweenness distributions of CGN.

The distributions of (A) degree and (B) stress (as well as its normalized counterpart ‘betweenness’) show a scale-free nature. Dotted lines show the power law fit with an exponent of −2.85 and −2.13, respectively. This indicates presence of promiscuously interacting proteins with high degrees and central mediators that play role in information dynamics across the network, respectively.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0049401.g004