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Neurotensin and CRH Interactions Augment Human Mast Cell Activation

Figure 1

NT stimulates degranulation of human mast cells.

(A) LAD2 mast cells and (B) hCBMCs were stimulated with NT for 30 min at 37°C. SP was used as a “positive” control to stimulate mast cell degranulation. The release of β-hexosaminidase (β-hex) was significantly elevated as compared to the control (n = 3; *p<0.01).

Figure 1

doi: https://doi.org/10.1371/journal.pone.0048934.g001