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Fertility and Pregnancy-Associated ß-Cell Proliferation in Mice Deficient in Proglucagon-Derived Peptides

Figure 2

Blood glucose and serum insulin levels in pregnant Gcggfp/gfp mice.

Blood glucose levels (A) (n = 49–51) and serum insulin levels (C) (n = 8–14) in ad libitum-fed Gcggfp/gfp mice during pregnancy. Fasting blood glucose levels (B) (n = 9–11) and serum insulin levels (D) (n = 6–14) in non-pregnant Gcggfp/gfp and pregnant Gcggfp/gfp mice. Open squares: Gcg+/+ and Gcggfp/+; closed squares: Gcggfp/gfp. Values are expressed as means±SEM. *p<0/05, **p<0.01, ***p<0.001.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0043745.g002