Evidence of Melanoma in Wild Marine Fish Populations
Transmission Electron Micrographs of different samples of P. leopardus exhibiting; (a) healthy tissue showing the two cell types (A & B) associated in the dermis along the collagenous basal membrane (CBM).
Cell A shows localisation of melanosomes and Cell B shows absence of melanosomes in the same area. (b) Lesion showing disorganisation of pleomorphic cells (A & B) with an increase in number and spread of melanosomes. This lesion is an example of a P. leopardus suffering from stage II melanoma, where the melanosomes are restricted to the dermis. Scale bars = 10 µm.