Lipo-Endomorphin-1 Derivatives with Systemic Activity against Neuropathic Pain without Producing Constipation
Figure 6
Insignificant antinociception produced by compounds 1 and 2.
The highest doses of compounds 1 and 2 did not produce pain relief at 16 µmol/kg after single bolus i.v. administration to CCI-rats. Each value represents mean (± SEM) (n = 6–8).