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Lipo-Endomorphin-1 Derivatives with Systemic Activity against Neuropathic Pain without Producing Constipation

Figure 3

Inhibition of forskolin-induced cAMP formation.

Dose-response curves for the inhibitory effects of compounds A) 1, 2, and 4; B) 1, and 3 on forskolin-stimulated cAMP formation in SH-SY5Y cells. Data presented are mean (± SEM) from three separate experiments, each performed in triplicate.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0041909.g003