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Calcium Channel Blockers, More than Diuretics, Enhance Vascular Protective Effects of Angiotensin Receptor Blockers in Salt-Loaded Hypertensive Rats

Figure 1

Effect on blood pressure of salt-loaded SHRSP.

Abbreviations used: Ve, vehicle-treated SHRSP; Ol, olmesartan-treated SHRSP; Az, azelnidipine-treated SHRSP; Hy, hydrochlorothiazide-treated SHRSP; Ol+Az, combined olmesartan and azelnidipine-treated SHRSP; Ol+Hy, combined olmesartan and hydrochlorothiazide-treated SHRSP; WKY, Wistar-Kyoto rats. Each value represents the mean ± SEM (n = 8 in Ve, n = 7 in Ol, n = 7 in Az, n = 4 in Hy, n = 7 in Ol+Az, n = 7 in Ol+Hy, n = 8 in WKY).

Figure 1