Uptake and Accumulation of Oxidized Low-Density Lipoprotein during Mycobacterium tuberculosis Infection in Guinea Pigs
Figure 5
Lung lesions in M. tuberculosis infected guinea pigs have increased expression of CD36.
A. The overall expression of CD36 in the lungs increases with time in guinea pigs sham-vaccinated with saline or BCG as determined by scoring of immunostained sections. The bars represent median values plus range (when present) for each group (n = 5). The asterisks denote statistically significant increase compared to the naive animals (* = p<0.05 and ** = p<0.01). The photomicrographs B and C represent immunostaining of CD36 predominantly within lung granulomas at 30 and 60 days of infection respectively (40×). The inserts (1000×) show intracellular staining within macrophages.