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Proof of Concept of Microbiome-Metabolome Analysis and Delayed Gluten Exposure on Celiac Disease Autoimmunity in Genetically At-Risk Infants

Figure 6

1H-NMR metabolomics analysis.

A. PCA analysis of metabolomic profiles (A). Relative concentration of major metabolites measured from stool NMR profiles in selected subjects over the 24-month study period (B–F). B. Succinate; C. Acetate; D. Lactate; E. Butyrate and F. Propionate. The chemical shift (ppm) value of each metabolite is indicated above each panel.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0033387.g006