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Proof of Concept of Microbiome-Metabolome Analysis and Delayed Gluten Exposure on Celiac Disease Autoimmunity in Genetically At-Risk Infants

Figure 4

Heatmap of relative abundance of bacterial phylum of longitudinal samples from DQ2+/DQ8+ infants analyzed in this study and those of Palmer et al. [28] (D), Color keys are indicated on the upper right corner.

A. Complete linkage clustering based on the phylum composition and abundance of GI microbiota. B. Color depicts the study and intervention group of the samples. C. Colors depict the time point at which the samples were collected. Time points D and E were omitted as no corresponding samples were collected in the Palmer et al. study [28].

Figure 4

doi: https://doi.org/10.1371/journal.pone.0033387.g004