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RAMTaB: Robust Alignment of Multi-Tag Bioimages

Figure 1

The RGB composite image before and after applying the RAMTaB: R,G and B channels belong to CD57, CD166 and DAPI tags respectively.

(a) and (b) respectively show composite image formed by using phase images Ij and fluorescence images Fj, before alignment, (c) and (d) show the RGB composite images after the images were aligned using the proposed framework. The red color fringes in (a) show the degree of misalignment among the three tags. These color fringes have been replaced by white and grey regions in (c) after alignment.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0030894.g001