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Combinations of Histone Modifications Mark Exon Inclusion Levels

Figure 3

Footprints of rules from the model.

The footprints are centred on intron-exon junctions (I/E) with examples of rules in the model from the (A) ‘Spliced out’ class (covers 358 exons, −6 pp accuracy gain over independent histone, referred to as S1 in Table 1), (B) ‘Spliced out’ (296, +5 pp, S3), (C) ‘Spliced out’ (260, +12 pp, S5) and (D) ‘Included’ (3738, −8 pp, I1). The number of reads normalized to sequence depth as left axis.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0029911.g003