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Combinations of Histone Modifications Mark Exon Inclusion Levels

Figure 1

Schematic representation of the constructed data set.

For each histone modification, e.g. H3K36me3, we deem it as present or absent in the region centred over the exon and the regions preceding and succeeding depending on if the histone modification pileup in such region is higher than a defined cut-off. This cut-off is specific for each histone modification since they were sequenced at difference depths.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0029911.g001