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Gene Regulatory Network Reconstruction Using Bayesian Networks, the Dantzig Selector, the Lasso and Their Meta-Analysis

Figure 6

Analysis of precision/recall of the meta-analysis approach for DREAM5 Challenge 3A with individuals/Network1 data.

Predicted gene regulations are classified into four groups depending on the label of the regulator and the target gene. A gene is labelled ‘cis’ if its marker has a cis-regulated effect on its expression level. Otherwise, gene is labelled ‘trans’. An edge between two ‘cis’ labelled genes is classified ‘cis cis’, between two ‘trans’ labelled genes: ‘trans trans’ and so on.

Figure 6