Browse Subject Areas

Click through the PLOS taxonomy to find articles in your field.

For more information about PLOS Subject Areas, click here.

< Back to Article

CATCHprofiles: Clustering and Alignment Tool for ChIP Profiles

Figure 2

The effect of CATCH alignment on H3K4me3 profile on a subset of ENCODE TSS.

A set of 241 promoter regions with high H3K4me3 was selected from the CATCH analysis of ENCODE TSS. The H3K4me3 signal is shown (a) aligned by the genomic position of the TSS disregarding the direction of the TSS (b) aligned by TSS and allowing mirroring of profiles to increase similarity of the patterns (c) by CATCH alignment without mirroring (d) by CATCH alignment and mirroring. The alignment becomes better and the average signal more localized when using both mirroring and CATCH alignment.

Figure 2