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CATCHprofiles: Clustering and Alignment Tool for ChIP Profiles

Figure 1

Example profile of PolII cluster with marks of active transcription.

The average profile pattern of cluster 12750 (containing 2093 profiles) from the CATCH clustering of PolII binding sites. The profile pattern has a high signal for both H3K4me3 and all the histone acetylation marks, which are known to correlate with active transcription. 81% of the profiles are within 1 kb of annotated Ensembl TSS, and of the remaining 389 regions, 253 were within 1 kb of Aceview predicted TSS.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0028272.g001