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Rohlin Distance and the Evolution of Influenza A Virus: Weak Attractors and Precursors

Figure 3

Clusters and time evolution for H1N1.

(upper part) Rohlin clusters time evolution for H1N1. (lower part) Hamming clusters time evolution for H1N1. The reference WHO sequences are shown by the corresponding symbols, as indicated in Table 2. In the upper part, we indicate the vaccine choice according to the WHO indication (up) and to buds criterion (lower). Green and red colors indicate right and wrong choice. In this case, some of the symbols does not correspond to a specific HI test, so they are indicated by a star and a pentagon. Notice the onset of the pandemic virus and the failure of the bud criterion after that line.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0027924.g003