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Rohlin Distance and the Evolution of Influenza A Virus: Weak Attractors and Precursors

Figure 2

Clusters and time evolution for H3N2.

(upper part) Rohlin clusters time evolution for H3N2. (lower part) Hamming clusters time evolution for H3N2. The reference WHO sequences are shown by the corresponding symbols and names, and the details are indicated in Table 1. In the upper part, we indicate the vaccine choice according to the WHO indication (up) and to buds criterion (lower). Green and red colors indicate right and wrong choice with respect to the corresponding analysis on the real circulating strain. A double color is used when more than one strain circulated in that year and the corresponding prediction agrees with one of the circulating strain.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0027924.g002