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The Role of PKR/eIF2α Signaling Pathway in Prognosis of Non-Small Cell Lung Cancer

Figure 4

The prognostic significance assessed by using Kaplan-Meier survival estimates and long-rank test.

A and C. Survival rate was significantly lower patients with low PKR or low p-PKR expression than in those with high PKR or high p-PKR expression on stage I (A) and all stages (C) (p = 0.001 and p = 0.001, respectively). B and D. Survival rate was also significantly lower in patients with low PKR or low p-eIF2α expression than in those with high PKR or high p-eIF2α expression on stage I (B) and all stages (D) (p = 0.001 and p = 0.001, respectively).

Figure 4

doi: https://doi.org/10.1371/journal.pone.0024855.g004